Single Cell Analysis
Current SNP, genomic analysis or proteomic assays require a large number of cells, thus limiting their uses in a variety of clinical settings where only a limited number of cells can be obtained. Furthermore, contamination by various types of cells may make analysis difficult or inaccurate in a clinical setting. Cases where single cell analysis would be invaluable include detection of rare events such as single cancer cells (before there are actual tumors) or analysis of cerebrospinal fluid.
We have developed a gel-based single-cell analysis system that allows the laboratory to detect SNPs, analyze genomic expression, and identify proteomic differences in a single cell with the aid of RAM/HSAM technology. This system allows rapid, high throughput analysis and miniaturization of devices and instruments with a significant reduction in assay cost.